STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3977D-serine dehydratase; Orthologue of E. coli dsdA (SDHD_ECOLI); Fasta hit to SDHD_ECOLI (442 aa), 89% identity in 442 aa overlap. (440 aa)    
Predicted Functional Partners:
STY3110
L-serine dehydratase 2 (L-serine deaminase 2); Fasta hit to TDCG_ECOLI (454 aa), 73% identity in 454 aa overlap; Fasta hit to SDHL_ECOLI (454 aa), 77% identity in 455 aa overlap; Orthologue of E. coli sdaB (SDHM_ECOLI); Fasta hit to SDHM_ECOLI (455 aa), 94% identity in 455 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.910
STY1956
L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.906
STY2430
Putative L-serine dehydratase; Fasta hit to SDHM_ECOLI (455 aa), 50% identity in 452 aa overlap; Fasta hit to TDCG_ECOLI (454 aa), 51% identity in 450 aa overlap; Paralogue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 49% identity in 453 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.906
tdcG
Similar to Escherichia coli L-serine dehydratase TdcG SW:TDCG_ECOLI () (454 aa) fasta scores: E(): 0, 86.6% id in 454 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.906
STY3427
Catabolic threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.906
STY3652
Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.906
STY3978
DsdX permease; Fasta hit to YJHF_ECOLI (449 aa), 34% identity in 445 aa overlap; Fasta hit to YGBN_ECOLI (454 aa), 30% identity in 455 aa overlap; Fasta hit to GNTT_ECOLI (437 aa), 35% identity in 440 aa overlap; Fasta hit to GNTP_ECOLI (447 aa), 33% identity in 453 aa overlap; Fasta hit to GNTU_ECOLI (446 aa), 34% identity in 443 aa overlap; Fasta hit to IDNT_ECOLI (439 aa), 33% identity in 437 aa overlap; Orthologue of E. coli dsdX (DSDX_ECOLI); Fasta hit to DSDX_ECOLI (445 aa), 93% identity in 445 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.
  
  
 0.893
STY3762
Similar to Rhizobium meliloti probable rhizopine catabolism regulatory protein MocR mocR SW:MOCR_RHIME (P49309) (493 aa) fasta scores: E(): 0, 33.9% id in 492 aa.
  
   
 0.835
STY1172
Putative 2-hydroxyacid dehydrogenase in phoh-csgg intergenic region; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
     
  0.800
STY1687
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
  0.800
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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