STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhjMProbable endoglucanase precursor; Hydrolyzes carboxymethylcellulose; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (369 aa)    
Predicted Functional Partners:
yhjO
Putative polysaccharide biosynthesis protein catalytic subunit; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix (By similarity).
 
  
 0.995
STY4182
Putative polysaccharide biosynthesis protein subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.
 
  
 0.995
yhjQ
Conserved hypothetical protein; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family.
 
   
 0.989
STY4178
Conserved hypothetical protein; Orthologue of E. coli yhjS (YHJS_ECOLI); Fasta hit to YHJS_ECOLI (523 aa), 80% identity in 519 aa overlap.
 
   
 0.978
STY4176
Putative membrane protein; Orthologue of E. coli yhjU (YHJU_ECOLI); Fasta hit to YHJU_ECOLI (559 aa), 85% identity in 559 aa overlap. N-terminus contains hydrophobic, probable membrane-spanning regions.
 
   
 0.975
STY4179
Conserved hypothetical protein; Orthologue of E. coli YHJR_ECOLI; Fasta hit to YHJR_ECOLI (62 aa), 77% identity in 60 aa overlap.
     
 0.952
STY4177
Putative membrane protein; Orthologue of E. coli YHJT_ECOLI; Fasta hit to YHJT_ECOLI (62 aa), 81% identity in 62 aa overlap. Contains an hydrophobic, possible membrane-spanning region.
     
 0.895
STY2396
Similar to Salmonella typhimurium periplasmic beta-glucosidase precursor SW:BGLX_SALTY (Q56078) (765 aa) fasta scores: E(): 0, 99.0% id in 765 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli bglX (BGLX_ECOLI); Fasta hit to BGLX_ECOLI (765 aa), 93% identity in 765 aa overlap; Belongs to the glycosyl hydrolase 3 family.
     
 0.813
ccmB1
Heme exporter protein B1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
      
 0.683
celB
PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
  
   
 0.666
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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