STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (477 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.999
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
 
 
 0.999
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.996
glgX
Glycogen operon protein; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
  
 0.993
malQ
4-alpha-glucanotransferase; Similar to Escherichia coli 4-alpha-glucanotransferase MalQ SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 0, 84.9% id in 694 aa, and to Haemophilus influenzae 4-alpha-glucanotransferase MalQ SW:MALQ_HAEIN (P45176) (699 aa) fasta scores: E(): 0, 41.1% id in 635 aa.
 
 
 0.967
STY4282
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.954
STY1505
Similar to Escherichia coli glycogen operon protein GlyX SW:GLGX_ECOLI (P15067; P76693) (657 aa) fasta scores: E(): 0, 48.8% id in 592 aa. Putative glycogen debranching protein; Belongs to the glycosyl hydrolase 13 family.
  
 0.883
STY1503
Putative hydrolase; Similar to Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase, putative dr0464 TR:Q9RX51 (EMBL:AE001905) (600 aa) fasta scores: E(): 0, 43.4% id in 509 aa, and to Rhizobium sp maltooligosyl trehalose trehalohydrolase treZ TR:Q53238 (EMBL:D78001) (596 aa) fasta scores: E(): 0, 39.4% id in 569 aa.
 
  
 0.796
adh
Alcohol dehydrogenase; Similar to Escherichia coli aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase adhE or ana SW:ADHE_ECOLI (P17547) (890 aa) fasta scores: E(): 0, 97.3% id in 892 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.755
STY0439
Maltodextrin glucosidase; Orthologue of E. coli malZ (MALZ_ECOLI); Fasta hit to MALZ_ECOLI (605 aa), 83% identity in 604 aa overlap; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.576
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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