node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_1200 | adhB | PFL_1200 | PFL_1399 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | Alcohol dehydrogenase II; Identified by similarity to SP:P06758; match to protein family HMM PF00465. | 0.962 |
PFL_1200 | pcd | PFL_1200 | PFL_0596 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | Piperideine-6-carboxylate dehydrogenase; Identified by similarity to GB:BAB19801.1; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.918 |
PFL_1836 | PFL_3068 | PFL_1836 | PFL_3068 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.910 |
PFL_1836 | PFL_4884 | PFL_1836 | PFL_4884 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.910 |
PFL_1836 | PFL_5009 | PFL_1836 | PFL_5009 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Putative 4-aminobutyrate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.910 |
PFL_1836 | acsA_1 | PFL_1836 | PFL_4522 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |
PFL_1836 | acsA_2 | PFL_1836 | PFL_5281 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |
PFL_1836 | fadB | PFL_1836 | PFL_1940 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Fatty oxidation complex, alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.957 |
PFL_1836 | pcd | PFL_1836 | PFL_0596 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Piperideine-6-carboxylate dehydrogenase; Identified by similarity to GB:BAB19801.1; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.916 |
PFL_3068 | PFL_1836 | PFL_3068 | PFL_1836 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | 0.910 |
PFL_3068 | PFL_4884 | PFL_3068 | PFL_4884 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.813 |
PFL_3068 | PFL_5009 | PFL_3068 | PFL_5009 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Putative 4-aminobutyrate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.813 |
PFL_3068 | acsA_1 | PFL_3068 | PFL_4522 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.923 |
PFL_3068 | acsA_2 | PFL_3068 | PFL_5281 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.922 |
PFL_3068 | fadB | PFL_3068 | PFL_1940 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Fatty oxidation complex, alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.910 |
PFL_3068 | pcd | PFL_3068 | PFL_0596 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Piperideine-6-carboxylate dehydrogenase; Identified by similarity to GB:BAB19801.1; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.930 |
PFL_4884 | PFL_1836 | PFL_4884 | PFL_1836 | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | 0.910 |
PFL_4884 | PFL_3068 | PFL_4884 | PFL_3068 | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.813 |
PFL_4884 | PFL_5009 | PFL_4884 | PFL_5009 | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative 4-aminobutyrate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.924 |
PFL_4884 | acsA_1 | PFL_4884 | PFL_4522 | Aminotransferase, class III; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.813 |