node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_0316 | cbpA | PFL_0316 | PFL_0628 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.835 |
PFL_0316 | clpA | PFL_0316 | PFL_3885 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | 0.588 |
PFL_0316 | dnaJ | PFL_0316 | PFL_0828 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.835 |
PFL_0316 | dnaK | PFL_0316 | PFL_0827 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.877 |
PFL_0316 | groL | PFL_0316 | PFL_4838 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.634 |
PFL_0316 | groS | PFL_0316 | PFL_4839 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.616 |
PFL_0316 | grpE | PFL_0316 | PFL_0826 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.611 |
PFL_0316 | htpG | PFL_0316 | PFL_1729 | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.878 |
cbpA | PFL_0316 | PFL_0628 | PFL_0316 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | 0.835 |
cbpA | clpA | PFL_0628 | PFL_3885 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | 0.665 |
cbpA | dnaK | PFL_0628 | PFL_0827 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.962 |
cbpA | groL | PFL_0628 | PFL_4838 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.814 |
cbpA | groS | PFL_0628 | PFL_4839 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.713 |
cbpA | grpE | PFL_0628 | PFL_0826 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.947 |
cbpA | htpG | PFL_0628 | PFL_1729 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.962 |
clpA | PFL_0316 | PFL_3885 | PFL_0316 | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719. | 0.588 |
clpA | cbpA | PFL_3885 | PFL_0628 | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.665 |
clpA | dnaJ | PFL_3885 | PFL_0828 | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.788 |
clpA | dnaK | PFL_3885 | PFL_0827 | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.863 |
clpA | groL | PFL_3885 | PFL_4838 | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by similarity to SP:P0ABH9; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.636 |