STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (434 aa)    
Predicted Functional Partners:
maiA
Maleylacetoacetate isomerase; Identified by similarity to SP:O43708; match to protein family HMM PF02798; match to protein family HMM TIGR01262.
 
 
 0.997
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263.
 
 0.993
fahA
Fumarylacetoacetase; Identified by similarity to SP:P25093; match to protein family HMM PF01557; match to protein family HMM PF09298; match to protein family HMM TIGR01266.
 
  
 0.990
PFL_5385
Putative 4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM PF01261.
 
 0.985
phhA
Phenylalanine-4-hydroxylase; Identified by similarity to SP:P30967; match to protein family HMM PF00351; match to protein family HMM TIGR01267.
 
  
 0.917
PFL_4358
Conserved hypothetical protein; Identified by match to protein family HMM PF07287.
 
 
 0.753
atuA
Acyclic terpene utilization protein AtuA; Identified by similarity to GB:AAG06274.1; similarity to GB:ABC69240.1; match to protein family HMM PF07287.
  
 
 0.720
phhB
4a-hydroxytetrahydrobiopterin dehydratase; Identified by match to protein family HMM PF01329.
  
  
 0.687
pobA
4-hydroxybenzoate 3-monooxygenase; Identified by similarity to SP:P20586; match to protein family HMM PF01494; match to protein family HMM TIGR02360.
 
  
 0.685
PFL_5909
FAH family protein; Identified by match to protein family HMM PF01557.
  
  
 0.670
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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