STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFL_1412Proline racemase family protein; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. (310 aa)    
Predicted Functional Partners:
PFL_1411
FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266.
 
 
 0.993
PFL_1409
Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF04324; match to protein family HMM PF07992.
 
  
 0.991
PFL_1410
2Fe-2S iron-sulfur cluster binding domain protein; Identified by match to protein family HMM PF00111.
 
  
  0.989
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.923
PFL_1413
Identified by match to protein family HMM PF00701; Belongs to the DapA family.
 
  
 0.872
PFL_1408
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF08448.
 
     0.857
PFL_1045
Identified by match to protein family HMM PF02423.
 
   
 0.764
aldH_1
NADP-dependent fatty aldehyde dehydrogenase; Identified by similarity to SP:Q56694; match to protein family HMM PF00171.
 
 
 0.750
PFL_1416
malate/L-lactate dehydrogenase family protein; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. May be involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline.
 
   
 0.748
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
      
 0.728
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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