node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_0542 | rlmM | PFL_0542 | PFL_1930 | Conserved hypothetical protein; Identified by match to protein family HMM PF06853. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.407 |
PFL_1547 | rlmM | PFL_1547 | PFL_1930 | Transporter, 10 TMS drug/metabolite exporter (DME) family; Identified by match to protein family HMM PF00892. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.474 |
PFL_3558 | rlmM | PFL_3558 | PFL_1930 | Putative oxidoreductase; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.470 |
PFL_5354 | rlmM | PFL_5354 | PFL_1930 | Type IV pilus assembly protein, PilZ family; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.407 |
PFL_5852 | rlmM | PFL_5852 | PFL_1930 | Conserved hypothetical protein; Identified by match to protein family HMM PF04241. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.606 |
acnA | rlmM | PFL_1929 | PFL_1930 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.552 |
ndpA_1 | rlmM | PFL_1060 | PFL_1930 | Nucleoid-associated protein NdpA; Identified by match to protein family HMM PF04245. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.443 |
ndpA_2 | rlmM | PFL_4665 | PFL_1930 | Nucleoid-associated protein NdpA; Identified by match to protein family HMM PF04245. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.467 |
queF | rlmM | PFL_1967 | PFL_1930 | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.458 |
rlmM | PFL_0542 | PFL_1930 | PFL_0542 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Conserved hypothetical protein; Identified by match to protein family HMM PF06853. | 0.407 |
rlmM | PFL_1547 | PFL_1930 | PFL_1547 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Transporter, 10 TMS drug/metabolite exporter (DME) family; Identified by match to protein family HMM PF00892. | 0.474 |
rlmM | PFL_3558 | PFL_1930 | PFL_3558 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Putative oxidoreductase; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913. | 0.470 |
rlmM | PFL_5354 | PFL_1930 | PFL_5354 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Type IV pilus assembly protein, PilZ family; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | 0.407 |
rlmM | PFL_5852 | PFL_1930 | PFL_5852 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Conserved hypothetical protein; Identified by match to protein family HMM PF04241. | 0.606 |
rlmM | acnA | PFL_1930 | PFL_1929 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.552 |
rlmM | ndpA_1 | PFL_1930 | PFL_1060 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Nucleoid-associated protein NdpA; Identified by match to protein family HMM PF04245. | 0.443 |
rlmM | ndpA_2 | PFL_1930 | PFL_4665 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Nucleoid-associated protein NdpA; Identified by match to protein family HMM PF04245. | 0.467 |
rlmM | queF | PFL_1930 | PFL_1967 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.458 |
rlmM | tusA | PFL_1930 | PFL_1931 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Sulfurtransferase TusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.518 |
tusA | rlmM | PFL_1931 | PFL_1930 | Sulfurtransferase TusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.518 |