STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshABGlutathione biosynthesis bifunctional protein: glutamate-cysteine ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate-- cysteine ligase type 1 family. Type 2 subfamily. (751 aa)    
Predicted Functional Partners:
gshA
Glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family.
 
  
0.949
bcaT
Branched-chain amino acid aminotransferase.
  
 
 0.919
pepN
Membrane alanine aminopeptidase (aminopeptidase N).
   
 
 0.909
glnA
Glutamate-ammonia ligase.
  
 
 0.882
cblB
Cystathionine beta-lyase / cystathionine gamma-lyase.
  
 
 0.873
cbs
Cystathionine beta-synthase.
    
 0.869
cblA3
Cystathionine beta-lyase.
    
 0.857
gdh
Glutamate dehydrogenase, NADP-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.817
gadB
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
 
 0.816
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
  0.812
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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