node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OB0061 | OB0062 | gene:10732223 | gene:10732224 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Hypothetical conserved protein; CDS_ID OB0062. | 0.880 |
OB0061 | OB0063 | gene:10732223 | gene:10732225 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.816 |
OB0061 | OB0077 | gene:10732223 | gene:10732240 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.712 |
OB0061 | OB1972 | gene:10732223 | gene:10734218 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | GTP-binding protein (elongation factor family); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.721 |
OB0061 | OB2495 | gene:10732223 | gene:10734747 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.774 |
OB0061 | OB2998 | gene:10732223 | gene:10735250 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.736 |
OB0061 | OB3480 | gene:10732223 | gene:10735732 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.895 |
OB0061 | frr | gene:10732223 | gene:10733829 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.680 |
OB0061 | rplY | gene:10732223 | gene:10732222 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.775 |
OB0061 | rpmA | gene:10732223 | gene:10734290 | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 50S ribosomal protein L27; CDS_ID OB2044; Belongs to the bacterial ribosomal protein bL27 family. | 0.753 |
OB0062 | OB0061 | gene:10732224 | gene:10732223 | Hypothetical conserved protein; CDS_ID OB0062. | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.880 |
OB0062 | OB0063 | gene:10732224 | gene:10732225 | Hypothetical conserved protein; CDS_ID OB0062. | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.691 |
OB0062 | rplY | gene:10732224 | gene:10732222 | Hypothetical conserved protein; CDS_ID OB0062. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.549 |
OB0063 | OB0061 | gene:10732225 | gene:10732223 | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.816 |
OB0063 | OB0062 | gene:10732225 | gene:10732224 | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Hypothetical conserved protein; CDS_ID OB0062. | 0.691 |
OB0063 | OB0077 | gene:10732225 | gene:10732240 | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.713 |
OB0063 | OB2495 | gene:10732225 | gene:10734747 | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.764 |
OB0063 | rplY | gene:10732225 | gene:10732222 | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.417 |
OB0077 | OB0061 | gene:10732240 | gene:10732223 | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Stage V sporulation protein C (peptidyl-tRNA hydrolase (PTH)); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.712 |
OB0077 | OB0063 | gene:10732240 | gene:10732225 | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.713 |