STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OB0629Negative regulator of sigma-B activity (switch protein/serine kinase, anti-sigma factor); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (158 aa)    
Predicted Functional Partners:
OB0628
Positive regulator of sigma-B activity (anti-anti-sigma factor); CDS_ID OB0628; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.999
OB0630
RNA polymerase general stress sigma factor (sigma B); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.997
OB0627
Indirect positive regulator of sigma-B activity (serine phosphatase); CDS_ID OB0627.
 
 
 0.974
OB0631
Indirect negative regulator of sigma-B activity (serine phosphatase); CDS_ID OB0631.
 
 
 0.959
OB0624
Positive regulator of sigma-B activity; CDS_ID OB0624.
 
 
 0.916
OB0625
Negative regulator of sigma-B activity (antagonist of RsbT); CDS_ID OB0625.
 
 
 0.914
sigF
Stage II sporulation protein AC (RNA polymerase sigma-F factor); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.898
OB0588
Protein kinase; CDS_ID OB0588.
 
 
 0.877
spoIIAA
Stage II sporulation protein AA protein (anti-sigma F factor antagonist); CDS_ID OB1841; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.877
OB0023
General stress protein 18 (GSP18); CDS_ID OB0023.
  
    0.819
Your Current Organism:
Oceanobacillus iheyensis
NCBI taxonomy Id: 221109
Other names: O. iheyensis HTE831, Oceanobacillus iheyensis HTE831, Oceanobacillus iheyensis str. HTE831, Oceanobacillus iheyensis strain HTE831, marine firmicute HTE831
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.