STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OB2476Glycerol uptake facilitator; CDS_ID OB2476; Belongs to the MIP/aquaporin (TC 1.A.8) family. (276 aa)    
Predicted Functional Partners:
OB2475
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
 
 0.993
OB2471
Glycerol-3-phosphate dehydrogenase; CDS_ID OB2471.
  
 0.957
OB2477
Transcriptional antiterminator of glycerol uptake operon; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.
 
    0.818
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.795
OB2474
Dihydroxyacetone kinase; CDS_ID OB2474.
 
  
 0.790
OB1508
Hypothetical conserved protein; CDS_ID OB1508.
    
 
 0.775
OB2472
Hypothetical conserved protein; CDS_ID OB2472.
 
  
 0.772
OB2682
Hypothetical conserved protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
    
 
 0.742
OB2473
Hypothetical conserved protein; CDS_ID OB2473.
 
  
 0.738
dnaJ
Heat shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]
    
 
 0.736
Your Current Organism:
Oceanobacillus iheyensis
NCBI taxonomy Id: 221109
Other names: O. iheyensis HTE831, Oceanobacillus iheyensis HTE831, Oceanobacillus iheyensis str. HTE831, Oceanobacillus iheyensis strain HTE831, marine firmicute HTE831
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.