node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
crp-2 | cyaA | MS1934 | MS0277 | Crp protein; cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.902 |
crp-2 | icc | MS1934 | MS1693 | Crp protein; cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.626 |
cyaA | crp-2 | MS0277 | MS1934 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Crp protein; cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.902 |
cyaA | hemY | MS0277 | MS0273 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | HemY protein; Uncharacterized enzyme of heme biosynthesis. | 0.824 |
cyaA | icc | MS0277 | MS1693 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.963 |
cyaA | mazG | MS0277 | MS0351 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | MazG protein; Predicted pyrophosphatase. | 0.900 |
cyaA | moaA | MS0277 | MS1021 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | MoaA protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.800 |
cyaA | ndk | MS0277 | MS0668 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Ndk protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
cyaA | nrdD | MS0277 | MS0633 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | NrdD protein; Oxygen-sensitive ribonucleoside-triphosphate reductase. | 0.915 |
cyaA | pykF-2 | MS0277 | MS1197 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | PykF protein; Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
cyaA | spoT | MS0277 | MS0241 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
cyaA | spoT-2 | MS0277 | MS1736 | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
hemY | cyaA | MS0273 | MS0277 | HemY protein; Uncharacterized enzyme of heme biosynthesis. | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.824 |
icc | crp-2 | MS1693 | MS1934 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Crp protein; cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.626 |
icc | cyaA | MS1693 | MS0277 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.963 |
icc | mazG | MS1693 | MS0351 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | MazG protein; Predicted pyrophosphatase. | 0.912 |
mazG | cyaA | MS0351 | MS0277 | MazG protein; Predicted pyrophosphatase. | CyaA protein; Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.900 |
mazG | icc | MS0351 | MS1693 | MazG protein; Predicted pyrophosphatase. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.912 |
mazG | moaA | MS0351 | MS1021 | MazG protein; Predicted pyrophosphatase. | MoaA protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.803 |
mazG | ndk | MS0351 | MS0668 | MazG protein; Predicted pyrophosphatase. | Ndk protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |