STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adkAdk protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)    
Predicted Functional Partners:
purB
PurB protein; Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.942
ndk
Ndk protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
 
 0.936
hpt
Hpt protein; Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.933
apt
Apt protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.924
nrdF
NrdF protein; Ribonucleotide reductase beta subunit.
     
 0.923
nrdA
NrdA protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.922
pykF-2
PykF protein; Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.921
surE
SurE protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.921
rplE
RplE protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
  
 0.912
mazG
MazG protein; Predicted pyrophosphatase.
    
  0.909
Your Current Organism:
Mannheimia succiniciproducens
NCBI taxonomy Id: 221988
Other names: Mannheimia succiniciproducens MBEL55E, Mannheimia succiniciproducens str. MBEL55E, [. succiniciproducens MBEL55E, [Mannheimia] succiniciproducens MBEL55E
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