STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFPyrF protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa)    
Predicted Functional Partners:
pyrE
PyrE protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.989
pyrR
PyrR protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
 
 
 0.987
upp
Upp protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.932
pyrH
PyrH protein; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.925
surE
SurE protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.916
udk
Udk protein; Uridine kinase.
  
 0.913
mazG
MazG protein; Predicted pyrophosphatase.
     
  0.900
ushA-2
UshA protein; 5'-nucleotidase/2', 3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
  0.900
MS1905
Unknown; Predicted hydrolases of the HAD superfamily.
   
 
  0.900
pyrD
PyrD protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.898
Your Current Organism:
Mannheimia succiniciproducens
NCBI taxonomy Id: 221988
Other names: Mannheimia succiniciproducens MBEL55E, Mannheimia succiniciproducens str. MBEL55E, [. succiniciproducens MBEL55E, [Mannheimia] succiniciproducens MBEL55E
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