node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MS1828 | lipA | MS1828 | MS1826 | Unknown; Belongs to the UPF0250 family. | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.706 |
MS1828 | lipB | MS1828 | MS1827 | Unknown; Belongs to the UPF0250 family. | LipB protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.772 |
aceF | lipA | MS1335 | MS1826 | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.482 |
aceF | lipB | MS1335 | MS1827 | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | LipB protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.556 |
aceF | lpd | MS1335 | MS1334 | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lpd protein; Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes. | 0.999 |
aceF | lplA | MS1335 | MS1058 | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate-protein ligase A. | 0.815 |
aceF | pta | MS1335 | MS0998 | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pta protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.947 |
aceF-2 | lipA | MS1354 | MS1826 | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.560 |
aceF-2 | lipB | MS1354 | MS1827 | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | LipB protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.544 |
aceF-2 | lpd | MS1354 | MS1334 | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lpd protein; Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes. | 0.998 |
aceF-2 | lplA | MS1354 | MS1058 | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoate-protein ligase A. | 0.800 |
aceF-2 | pta | MS1354 | MS0998 | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Pta protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.497 |
guaA | lipA | MS0772 | MS1826 | GuaA protein; Catalyzes the synthesis of GMP from XMP. | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.475 |
guaA | obg | MS0772 | MS1594 | GuaA protein; Catalyzes the synthesis of GMP from XMP. | Obg protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.450 |
guaA | pta | MS0772 | MS0998 | GuaA protein; Catalyzes the synthesis of GMP from XMP. | Pta protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.718 |
lipA | MS1828 | MS1826 | MS1828 | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Unknown; Belongs to the UPF0250 family. | 0.706 |
lipA | aceF | MS1826 | MS1335 | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | AceF protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.482 |
lipA | aceF-2 | MS1826 | MS1354 | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | AceF protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.560 |
lipA | guaA | MS1826 | MS0772 | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | GuaA protein; Catalyzes the synthesis of GMP from XMP. | 0.475 |
lipA | lipB | MS1826 | MS1827 | LipA protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | LipB protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.999 |