node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSE_0318 | NSE_0817 | NSE_0318 | NSE_0817 | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | NifU-like domain protein; Identified by match to protein family HMM PF01106. | 0.492 |
NSE_0318 | lipA | NSE_0318 | NSE_0322 | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.612 |
NSE_0318 | pdxJ | NSE_0318 | NSE_0320 | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.498 |
NSE_0318 | yajC | NSE_0318 | NSE_0319 | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.407 |
NSE_0323 | lipA | NSE_0323 | NSE_0322 | Identified by match to protein family HMM PF03364. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.523 |
NSE_0323 | rpmB | NSE_0323 | NSE_0321 | Identified by match to protein family HMM PF03364. | Ribosomal protein L28; Identified by match to protein family HMM PF00830; match to protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family. | 0.462 |
NSE_0817 | NSE_0318 | NSE_0817 | NSE_0318 | NifU-like domain protein; Identified by match to protein family HMM PF01106. | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | 0.492 |
NSE_0817 | lipA | NSE_0817 | NSE_0322 | NifU-like domain protein; Identified by match to protein family HMM PF01106. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.542 |
guaA | lipA | NSE_0887 | NSE_0322 | GMP synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF01171; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.534 |
guaA | nrdA | NSE_0887 | NSE_0411 | GMP synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF01171; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.841 |
guaA | pdxJ | NSE_0887 | NSE_0320 | GMP synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF01171; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.536 |
guaA | yajC | NSE_0887 | NSE_0319 | GMP synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF01171; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.607 |
lipA | NSE_0318 | NSE_0322 | NSE_0318 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | 0.612 |
lipA | NSE_0323 | NSE_0322 | NSE_0323 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Identified by match to protein family HMM PF03364. | 0.523 |
lipA | NSE_0817 | NSE_0322 | NSE_0817 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | NifU-like domain protein; Identified by match to protein family HMM PF01106. | 0.542 |
lipA | guaA | NSE_0322 | NSE_0887 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | GMP synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF01171; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | 0.534 |
lipA | lipB | NSE_0322 | NSE_0100 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.994 |
lipA | nrdA | NSE_0322 | NSE_0411 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.692 |
lipA | pdxJ | NSE_0322 | NSE_0320 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.572 |
lipA | rpmB | NSE_0322 | NSE_0321 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Ribosomal protein L28; Identified by match to protein family HMM PF00830; match to protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family. | 0.788 |