node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSE_0356 | NSE_0735 | NSE_0356 | NSE_0735 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | 0.498 |
NSE_0356 | dnaN | NSE_0356 | NSE_0170 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.960 |
NSE_0356 | polA | NSE_0356 | NSE_0675 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | DNA polymerase I; Identified by similarity to SP:O34996; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593. | 0.808 |
NSE_0356 | recA | NSE_0356 | NSE_0530 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.976 |
NSE_0356 | rpoA | NSE_0356 | NSE_0289 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.476 |
NSE_0356 | topA | NSE_0356 | NSE_0594 | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.795 |
NSE_0377 | NSE_0735 | NSE_0377 | NSE_0735 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | 0.960 |
NSE_0377 | dnaN | NSE_0377 | NSE_0170 | Hypothetical protein; Identified by Glimmer2; putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
NSE_0377 | polA | NSE_0377 | NSE_0675 | Hypothetical protein; Identified by Glimmer2; putative. | DNA polymerase I; Identified by similarity to SP:O34996; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593. | 0.974 |
NSE_0377 | recA | NSE_0377 | NSE_0530 | Hypothetical protein; Identified by Glimmer2; putative. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.910 |
NSE_0377 | topA | NSE_0377 | NSE_0594 | Hypothetical protein; Identified by Glimmer2; putative. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.906 |
NSE_0735 | NSE_0356 | NSE_0735 | NSE_0356 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580. | 0.498 |
NSE_0735 | NSE_0377 | NSE_0735 | NSE_0377 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | Hypothetical protein; Identified by Glimmer2; putative. | 0.960 |
NSE_0735 | dnaN | NSE_0735 | NSE_0170 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
NSE_0735 | polA | NSE_0735 | NSE_0675 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | DNA polymerase I; Identified by similarity to SP:O34996; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593. | 0.998 |
NSE_0735 | recA | NSE_0735 | NSE_0530 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.866 |
NSE_0735 | topA | NSE_0735 | NSE_0594 | Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.729 |
acpP | dnaN | NSE_0452 | NSE_0170 | Acyl carrier protein; Identified by similarity to SP:P80922. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.543 |
acpP | polA | NSE_0452 | NSE_0675 | Acyl carrier protein; Identified by similarity to SP:P80922. | DNA polymerase I; Identified by similarity to SP:O34996; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593. | 0.860 |
acpP | recA | NSE_0452 | NSE_0530 | Acyl carrier protein; Identified by similarity to SP:P80922. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.879 |