STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSE_0967Phage uncharacterized protein; Identified by match to protein family HMM TIGR01630. (465 aa)    
Predicted Functional Partners:
NSE_0966
Conserved domain protein; Identified by similarity to GB:BAB54269.1.
       0.552
pqqC
Coenzyme PQQ synthesis protein C; Identified by similarity to SP:Q9L3B2; match to protein family HMM PF05312.
  
     0.505
NSE_0647
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.493
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.489
NSE_0542
RDD family protein; Identified by match to protein family HMM PF06271.
  
     0.469
NSE_0005
Iron-binding protein; Identified by similarity to GB:AAD03802.1; match to protein family HMM PF01547.
      
 0.468
NSE_0007
Phage portal protein, HK97 family; Identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537.
 
  
 0.416
NSE_0860
Type IV secretion system protein, VirB6 family; Identified by match to protein family HMM PF04610.
  
     0.405
Your Current Organism:
Neorickettsia sennetsu
NCBI taxonomy Id: 222891
Other names: N. sennetsu str. Miyayama, Neorickettsia sennetsu Miyayama, Neorickettsia sennetsu str. Miyayama
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