node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55366.1 | alg8 | PSPTO_1847 | PSPTO_1242 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | 0.762 |
AAO55366.1 | algG | PSPTO_1847 | PSPTO_1238 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate biosynthesis protein AlgG; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity). | 0.774 |
AAO55366.1 | algJ | PSPTO_1847 | PSPTO_1234 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate biosynthesis protein AlgJ; Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.767 |
AAO55366.1 | algK | PSPTO_1847 | PSPTO_1240 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate biosynthesis protein AlgK; May be involved in the polymerization of mannuronate to alginate. | 0.774 |
AAO55366.1 | algL | PSPTO_1847 | PSPTO_1236 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. | 0.776 |
AAO55366.1 | algX | PSPTO_1847 | PSPTO_1237 | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity). | 0.774 |
alg44 | alg8 | PSPTO_1241 | PSPTO_1242 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | 0.995 |
alg44 | algD | PSPTO_1241 | PSPTO_1243 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | GDP-mannose 6-dehydrogenase AlgD; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.974 |
alg44 | algE | PSPTO_1241 | PSPTO_1239 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgE; Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore. | 0.954 |
alg44 | algG | PSPTO_1241 | PSPTO_1238 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgG; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity). | 0.993 |
alg44 | algI | PSPTO_1241 | PSPTO_1235 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgI; Together with AlgJ and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.820 |
alg44 | algJ | PSPTO_1241 | PSPTO_1234 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgJ; Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.819 |
alg44 | algK | PSPTO_1241 | PSPTO_1240 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgK; May be involved in the polymerization of mannuronate to alginate. | 0.960 |
alg44 | algL | PSPTO_1241 | PSPTO_1236 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. | 0.933 |
alg44 | algX | PSPTO_1241 | PSPTO_1237 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity). | 0.935 |
alg8 | AAO55366.1 | PSPTO_1242 | PSPTO_1847 | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Transcriptional repressor, putative; See PMID:20190049 for expression data; similar to GP:6759952; identified by sequence similarity; putative. | 0.762 |
alg8 | alg44 | PSPTO_1242 | PSPTO_1241 | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | 0.995 |
alg8 | algD | PSPTO_1242 | PSPTO_1243 | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | GDP-mannose 6-dehydrogenase AlgD; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.985 |
alg8 | algE | PSPTO_1242 | PSPTO_1239 | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate biosynthesis protein AlgE; Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore. | 0.928 |
alg8 | algG | PSPTO_1242 | PSPTO_1238 | Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate biosynthesis protein AlgG; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity). | 0.997 |