STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
algDGDP-mannose 6-dehydrogenase AlgD; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)    
Predicted Functional Partners:
alg8
Alginate biosynthesis protein Alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid.
 
 
 0.985
algA
Alginate biosynthesis protein AlgA; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
 
 
 0.979
alg44
Alginate biosynthesis protein Alg44; Required for alginate biosynthesis.
  
 
 0.974
AAO57005.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase PslB; See PMID:20190049 for expression data; similar to GP:3510759; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.959
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
  
 0.925
uxuB
D-mannonate oxidoreductase; Similar to SP:P39160; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P39160, identified by sequence similarity, putative; Belongs to the mannitol dehydrogenase family.
     
 0.851
xylA
Xylose isomerase; Similar to GP:43314; identified by sequence similarity; putative; Belongs to the xylose isomerase family.
     
 0.806
AAO54490.1
Phosphotransferase system, fructose-specific IIBC component; See PMID:20190049 for expression data.
     
 0.803
algG
Alginate biosynthesis protein AlgG; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity).
 
  
 0.802
AAO56203.1
Fructokinase; Similar to GP:2293420; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:2293420, identified by sequence similarity, putative.
    
  0.802
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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