node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55795.1 | AAO55936.1 | PSPTO_2281 | PSPTO_2427 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | 0.911 |
AAO55795.1 | AAO58385.1 | PSPTO_2281 | PSPTO_4957 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | ACT domain protein/phosphoserine phosphatase SerB; See PMID:20190049 for expression data. | 0.929 |
AAO55795.1 | glyA-1 | PSPTO_2281 | PSPTO_0461 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
AAO55795.1 | glyA-2 | PSPTO_2281 | PSPTO_4632 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
AAO55795.1 | hom | PSPTO_2281 | PSPTO_1480 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Homoserine dehydrogenase; See PMID:20190049 for expression data. | 0.926 |
AAO55795.1 | sdaA | PSPTO_2281 | PSPTO_1886 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | L-serine dehydratase 1; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF03313; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.908 |
AAO55795.1 | serC | PSPTO_2281 | PSPTO_1746 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.929 |
AAO55795.1 | thrB | PSPTO_2281 | PSPTO_0346 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Homoserine kinase; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01636; Belongs to the pseudomonas-type ThrB family. | 0.917 |
AAO55795.1 | thrC | PSPTO_2281 | PSPTO_1481 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Threonine synthase; See PMID:20190049 for expression data. | 0.914 |
AAO55795.1 | trpB | PSPTO_2281 | PSPTO_0158 | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
AAO55936.1 | AAO55795.1 | PSPTO_2427 | PSPTO_2281 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | 0.911 |
AAO55936.1 | AAO58385.1 | PSPTO_2427 | PSPTO_4957 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | ACT domain protein/phosphoserine phosphatase SerB; See PMID:20190049 for expression data. | 0.943 |
AAO55936.1 | glyA-1 | PSPTO_2427 | PSPTO_0461 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
AAO55936.1 | glyA-2 | PSPTO_2427 | PSPTO_4632 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
AAO55936.1 | hom | PSPTO_2427 | PSPTO_1480 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Homoserine dehydrogenase; See PMID:20190049 for expression data. | 0.538 |
AAO55936.1 | sdaA | PSPTO_2427 | PSPTO_1886 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | L-serine dehydratase 1; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF03313; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.939 |
AAO55936.1 | serC | PSPTO_2427 | PSPTO_1746 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.443 |
AAO55936.1 | trpB | PSPTO_2427 | PSPTO_0158 | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.910 |
AAO58385.1 | AAO55795.1 | PSPTO_4957 | PSPTO_2281 | ACT domain protein/phosphoserine phosphatase SerB; See PMID:20190049 for expression data. | Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine. | 0.929 |
AAO58385.1 | AAO55936.1 | PSPTO_4957 | PSPTO_2427 | ACT domain protein/phosphoserine phosphatase SerB; See PMID:20190049 for expression data. | Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. | 0.943 |