STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (434 aa)    
Predicted Functional Partners:
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by match to PFAM protein family HMM PF00903; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00903.
 
 0.991
fahA
Fumarylacetoacetase; See PMID:20190049 for expression data.
 
  
 0.990
maiA
Maleylacetoacetate isomerase; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02798.
 
 
 0.989
AAO55858.1
4-hydroxyphenylpyruvate dioxygenase, putative; See PMID:20190049 for expression data; similar to GP:15141381; identified by sequence similarity; putative.
 
 0.984
phhA
Phenylalanine-4-hydroxylase; Identified by match to TIGR protein family HMM TIGR01270.
 
  
 0.880
AAO58718.1
Fumarylacetoacetate hydrolase family protein; See PMID:20190049 for expression data.
  
  
 0.703
cmaC
Coronamic acid synthetase CmaC; Catalyses formation of the cyclopropyl ring from the gamma-Cl-L-allo-isoleucine product of the CmaB reaction during coronamic acid biosynthesis; see PMID: 16121186; see PMID:20190049 for expression data; catalyses formation of the cyclopropyl ring from the gamma-Cl-L-allo-isoleucine product of the CmaB reaction during coronamic acid biosynthesis, see PMID: 16121186.
  
 
 0.679
phhB
Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA (By similarity); Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
  
  
 0.659
AAO57027.1
Transcriptional regulator, IclR family.
  
  
 0.636
AAO56239.1
Carboxyl transferase domain protein; Similar to GP:15159867; identified by sequence similarity; putative.
 
  
 0.494
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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