node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55215.1 | cobB2 | PSPTO_1695 | PSPTO_1704 | MazG family protein; See PMID:20190049 for expression data. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
AAO55215.1 | cobB4 | PSPTO_1695 | PSPTO_4675 | MazG family protein; See PMID:20190049 for expression data. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
AAO55215.1 | nadD | PSPTO_1695 | PSPTO_4828 | MazG family protein; See PMID:20190049 for expression data. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
AAO55215.1 | nadE | PSPTO_1695 | PSPTO_4922 | MazG family protein; See PMID:20190049 for expression data. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.900 |
AAO55215.1 | nudC | PSPTO_1695 | PSPTO_2720 | MazG family protein; See PMID:20190049 for expression data. | mutT/nudix family protein; See PMID:20190049 for expression data; similar to GP:3549119; identified by sequence similarity; putative. | 0.911 |
AAO55215.1 | pntB | PSPTO_1695 | PSPTO_5464 | MazG family protein; See PMID:20190049 for expression data. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
AAO55215.1 | ppnK | PSPTO_1695 | PSPTO_3793 | MazG family protein; See PMID:20190049 for expression data. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.902 |
AAO55215.1 | sthA | PSPTO_1695 | PSPTO_2106 | MazG family protein; See PMID:20190049 for expression data. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.919 |
AAO57260.1 | AAO57261.1 | PSPTO_3791 | PSPTO_3792 | Rhomboid family protein; See PMID:20190049 for expression data; similar to GP:9949195, and GP:9949195; identified by sequence similarity; putative. | Serine/threonine protein phosphatase; See PMID:20190049 for expression data; similar to GP:15020692; identified by sequence similarity; putative. | 0.851 |
AAO57260.1 | ppnK | PSPTO_3791 | PSPTO_3793 | Rhomboid family protein; See PMID:20190049 for expression data; similar to GP:9949195, and GP:9949195; identified by sequence similarity; putative. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.772 |
AAO57261.1 | AAO57260.1 | PSPTO_3792 | PSPTO_3791 | Serine/threonine protein phosphatase; See PMID:20190049 for expression data; similar to GP:15020692; identified by sequence similarity; putative. | Rhomboid family protein; See PMID:20190049 for expression data; similar to GP:9949195, and GP:9949195; identified by sequence similarity; putative. | 0.851 |
AAO57261.1 | ppnK | PSPTO_3792 | PSPTO_3793 | Serine/threonine protein phosphatase; See PMID:20190049 for expression data; similar to GP:15020692; identified by sequence similarity; putative. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.795 |
cobB2 | AAO55215.1 | PSPTO_1704 | PSPTO_1695 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | MazG family protein; See PMID:20190049 for expression data. | 0.901 |
cobB2 | cobB4 | PSPTO_1704 | PSPTO_4675 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.925 |
cobB2 | nadD | PSPTO_1704 | PSPTO_4828 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.914 |
cobB2 | nadE | PSPTO_1704 | PSPTO_4922 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.911 |
cobB2 | nudC | PSPTO_1704 | PSPTO_2720 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | mutT/nudix family protein; See PMID:20190049 for expression data; similar to GP:3549119; identified by sequence similarity; putative. | 0.906 |
cobB2 | pntB | PSPTO_1704 | PSPTO_5464 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
cobB2 | ppnK | PSPTO_1704 | PSPTO_3793 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.909 |
cobB2 | sthA | PSPTO_1704 | PSPTO_2106 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.907 |