STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAO57591.1DNA ligase, ATP-dependent; Similar to GP:15155825; identified by sequence similarity; putative. (571 aa)    
Predicted Functional Partners:
AAO57590.1
Conserved hypothetical protein; Similar to GP:15155824; identified by sequence similarity; putative.
 
 0.989
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.937
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.911
ligB
DNA ligase, NAD-dependent, putative; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
    
 0.909
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.852
AAO57598.1
Conserved hypothetical protein; Identified by match to TIGR protein family HMM TIGR00024.
 
   
 0.850
AAO57597.1
Helicase domain protein; Similar to GP:14025425; identified by sequence similarity; putative.
 
    0.835
AAO56939.1
DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative.
 
   
 0.704
polB
DNA polymerase II; Similar to SP:P21189; identified by sequence similarity; putative.
   
 0.665
holB
DNA polymerase III, delta prime subunit; See PMID:20190049 for expression data; similar to SP:P28631, GB:Z32564, GB:U08470, GB:U08471, GB:Z32633, SP:P14207, SP:P41439, PID:473236, PID:474061, PID:478885, and PID:478887; identified by sequence similarity; putative.
   
 0.658
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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