STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas2CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (92 aa)    
Predicted Functional Partners:
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
SFP59230.1
CRISPR-associated exonuclease, Cas4 family.
 
 
 
 0.997
SFP59182.1
CRISPR-associated protein, Cas5h family.
 
   
 0.932
SFP59184.1
CRISPR-associated endonuclease/helicase Cas3.
 
  
 0.931
SFP59141.1
CRISPR-associated protein, Csh2 family.
 
   
 0.914
SFP59029.1
CRISPR associated protein Cas6.
     
 0.621
SFP38762.1
DNA-binding protein HU-beta; Belongs to the bacterial histone-like protein family.
    
 
 0.608
SFP59105.1
Hypothetical protein.
       0.557
SFP23900.1
Recombination protein RecT.
  
   
 0.501
SFP59059.1
Hypothetical protein.
       0.424
Your Current Organism:
Hydrogenimonas thermophila
NCBI taxonomy Id: 223786
Other names: ATCC BAA-737, H. thermophila, Hydrogenimonas thermophila Takai et al. 2004, JCM 11971, strain EP1-55-1%
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.