STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaaLConserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function (74 aa)    
Predicted Functional Partners:
recR
May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
       0.863
yaaK
Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
       0.843
dnaX
Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
 
     0.824
bofA
Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K
 
     0.790
yqhP
Conserved hypothetical protein; Uncharacterized protein YqhP; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.746
yqzK
Conserved hypothetical protein; Uncharacterized membrane protein YqzK; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.715
ytrI
Protein involved in sporulation; Involved in sporulation
  
     0.711
yphE
Conserved hypothetical protein; Uncharacterized protein YphE; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.710
yppG
Conserved hypothetical protein; Uncharacterized protein YppG; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.704
ytzC
Conserved hypothetical protein; Uncharacterized protein YtzC; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.701
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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