node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bofA | dnaX | BSU00230 | BSU00190 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | 0.700 |
bofA | recR | BSU00230 | BSU00210 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.734 |
bofA | yaaK | BSU00230 | BSU00200 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | 0.694 |
bofA | yaaL | BSU00230 | BSU00220 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | 0.790 |
bofA | yqzK | BSU00230 | BSU23519 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | Conserved hypothetical protein; Uncharacterized membrane protein YqzK; Evidence 4: Homologs of previously reported genes of unknown function | 0.698 |
bofA | ytrI | BSU00230 | BSU29240 | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | Protein involved in sporulation; Involved in sporulation | 0.714 |
dnaX | bofA | BSU00190 | BSU00230 | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | 0.700 |
dnaX | recR | BSU00190 | BSU00210 | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.984 |
dnaX | yaaK | BSU00190 | BSU00200 | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | 0.910 |
dnaX | yaaL | BSU00190 | BSU00220 | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | 0.824 |
recR | bofA | BSU00210 | BSU00230 | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | 0.734 |
recR | dnaX | BSU00210 | BSU00190 | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | 0.984 |
recR | yaaK | BSU00210 | BSU00200 | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | 0.943 |
recR | yaaL | BSU00210 | BSU00220 | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | 0.863 |
yaaK | bofA | BSU00200 | BSU00230 | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | 0.694 |
yaaK | dnaX | BSU00200 | BSU00190 | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | 0.910 |
yaaK | recR | BSU00200 | BSU00210 | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.943 |
yaaK | yaaL | BSU00200 | BSU00220 | Nucleoid-associated protein yaak; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | 0.843 |
yaaL | bofA | BSU00220 | BSU00230 | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | Inhibitor of the pro-sigma(k) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K | 0.790 |
yaaL | dnaX | BSU00220 | BSU00190 | Conserved hypothetical protein; Uncharacterized protein YaaL; Evidence 4: Homologs of previously reported genes of unknown function | Dna polymerase iii (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | 0.824 |