node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cwlO | yabE | BSU34800 | BSU00400 | Secreted cell wall DL-endopeptidase; The C-terminal part of CwlO shows a cell wall hydrolytic DL- endopeptidase activity; Belongs to the peptidase C40 family. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.679 |
ksgA | rnmV | BSU00420 | BSU00410 | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | 0.987 |
ksgA | yabD | BSU00420 | BSU00390 | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.957 |
ksgA | yabE | BSU00420 | BSU00400 | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.801 |
rnmV | ksgA | BSU00410 | BSU00420 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.987 |
rnmV | yabD | BSU00410 | BSU00390 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.709 |
rnmV | yabE | BSU00410 | BSU00400 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.776 |
sbp | yabE | BSU15270 | BSU00400 | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.648 |
sbp | ylxW | BSU15270 | BSU15250 | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | Conserved hypothetical protein; May be involved in cell division and sporulation. Belongs to the UPF0749 family. | 0.985 |
sbp | ylxX | BSU15270 | BSU15260 | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.995 |
txpA | yabE | BSU26050 | BSU00400 | Conserved unknown protein (fragment); Toxic component of a type I toxin-antitoxin (TA) system. Overexpression of txpA causes cell lysis; the TxpA protein has been suggested to act on the cell membrane or might possibly block cell wall synthesis. Overexpression in E.coli is not toxic. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.750 |
xkdP | yabE | BSU12690 | BSU00400 | Putative PBSX prophage murein binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.672 |
yabD | ksgA | BSU00390 | BSU00420 | Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.957 |
yabD | rnmV | BSU00390 | BSU00410 | Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | 0.709 |
yabD | yabE | BSU00390 | BSU00400 | Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.845 |
yabE | cwlO | BSU00400 | BSU34800 | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Secreted cell wall DL-endopeptidase; The C-terminal part of CwlO shows a cell wall hydrolytic DL- endopeptidase activity; Belongs to the peptidase C40 family. | 0.679 |
yabE | ksgA | BSU00400 | BSU00420 | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.801 |
yabE | rnmV | BSU00400 | BSU00410 | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini. | 0.776 |
yabE | sbp | BSU00400 | BSU15270 | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.648 |
yabE | txpA | BSU00400 | BSU26050 | Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Conserved unknown protein (fragment); Toxic component of a type I toxin-antitoxin (TA) system. Overexpression of txpA causes cell lysis; the TxpA protein has been suggested to act on the cell membrane or might possibly block cell wall synthesis. Overexpression in E.coli is not toxic. | 0.750 |