node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
citA | citZ | BSU09440 | BSU29140 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 0.839 |
citA | fumC | BSU09440 | BSU33040 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | 0.971 |
citA | gabD | BSU09440 | BSU03910 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate | 0.862 |
citA | mdh | BSU09440 | BSU29120 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate | 0.973 |
citA | mmgD | BSU09440 | BSU24140 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 2-methylcitrate synthase/citrate synthase III; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles . Has both 2-methylcitrate synthase and citrate synthase activities. Catalyzes the condensation of propionyl-CoA and oxaloacetate to yield 2-methylcitrate (2-MC) and CoA, and the condensation of acetyl-CoA and oxaloacetate to yield citrate and CoA . Has 2.3-fold higher activity as a 2-methylcitrate synthase . Catalyzes the formation of either (2S,3R)- or (2R,3S)-2-methylcitrate | 0.832 |
citA | sdhA | BSU09440 | BSU28440 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase flavoprotein subunit; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme | 0.851 |
citA | sdhB | BSU09440 | BSU28430 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase / fumarate reductase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family | 0.763 |
citA | sdhC | BSU09440 | BSU28450 | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; Di-heme cytochrome of the succinate dehydrogenase complex | 0.614 |
citZ | citA | BSU29140 | BSU09440 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 0.839 |
citZ | fumC | BSU29140 | BSU33040 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | 0.976 |
citZ | gabD | BSU29140 | BSU03910 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate | 0.855 |
citZ | mdh | BSU29140 | BSU29120 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate | 0.995 |
citZ | mmgD | BSU29140 | BSU24140 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 2-methylcitrate synthase/citrate synthase III; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles . Has both 2-methylcitrate synthase and citrate synthase activities. Catalyzes the condensation of propionyl-CoA and oxaloacetate to yield 2-methylcitrate (2-MC) and CoA, and the condensation of acetyl-CoA and oxaloacetate to yield citrate and CoA . Has 2.3-fold higher activity as a 2-methylcitrate synthase . Catalyzes the formation of either (2S,3R)- or (2R,3S)-2-methylcitrate | 0.836 |
citZ | sdhA | BSU29140 | BSU28440 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase flavoprotein subunit; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme | 0.850 |
citZ | sdhB | BSU29140 | BSU28430 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase / fumarate reductase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family | 0.802 |
citZ | sdhC | BSU29140 | BSU28450 | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; Di-heme cytochrome of the succinate dehydrogenase complex | 0.638 |
fumC | citA | BSU33040 | BSU09440 | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | Citrate synthase i; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 0.971 |
fumC | citZ | BSU33040 | BSU29140 | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | Citrate synthase ii; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect | 0.976 |
fumC | gabD | BSU33040 | BSU03910 | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate | 0.855 |
fumC | mdh | BSU33040 | BSU29120 | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate | 0.995 |