STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydeNAlpha/beta hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RBBP9 family. (190 aa)    
Predicted Functional Partners:
estA
Secreted alkaliphilic lipase; Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups. Belongs to the AB hydrolase superfamily.
      
 0.980
estB
Secreted esterase / lipase; An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8:0). Active against p- nitrophenylesters with fatty acid chain lengths from C6 to C18.
      
 0.919
rsbQ
Regulator of RsbP phosphatase; Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for RsbP phosphatase activity; Belongs to the AB hydrolase superfamily.
      
 0.919
ybfK
Carboxylesterase NP; Shows carboxylesterase activity in vitro.
      
 0.891
nap
Carboxylesterase NP; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily.
      
 0.848
rhgT
Rhamnogalacturonan acetylesterase; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity, and shows strong preference for glucose pentaacetate, beta-naphthylacetate, and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan.
      
 0.847
pnbA
Para-nitrobenzyl esterase (intracellular esterase B); Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.845
yesY
Rhamnogalacturonan acetylesterase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates. Belongs to the 'GDSL' lipolytic enzyme family.
      
 0.830
ydzF
Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
    0.823
rsbP
Serine phosphatase; Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress.
      
 0.756
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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