STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yisNConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (195 aa)    
Predicted Functional Partners:
putC
1-pyrroline-5-carboxylate dehydrogenase; Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
      
 0.578
asnO
Asparagine synthetase; Asparagine synthetase involved in sporulation.
  
    0.559
phoD
Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
      
 0.485
argI
Arginase; Involved in the catabolism of arginine. Belongs to the arginase family.
      
 0.483
yueD
Putative aromatic compound reductase; Reduces benzil stereospecifically to (S)-benzoin.
      
 0.471
ykuE
Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallophosphoesterase superfamily.
      
 0.422
pdhD
Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.420
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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