Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| abbA | abrB | BSU14120 | BSU00370 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | 0.838 |
| abbA | mstX | BSU14120 | BSU31321 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer. | 0.687 |
| abbA | sinI | BSU14120 | BSU24600 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | 0.682 |
| abbA | sinR | BSU14120 | BSU24610 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...] | 0.429 |
| abbA | slrA | BSU14120 | BSU38229 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Anti-repressor of SlrR; Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation. | 0.483 |
| abbA | spo0A | BSU14120 | BSU24220 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.510 |
| abbA | veg | BSU14120 | BSU00440 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Conserved hypothetical protein; Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity, independently of the SinI, SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation. | 0.754 |
| abbA | ykuK | BSU14120 | BSU14110 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative RNAse; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.589 |
| abbA | ykuL | BSU14120 | BSU14130 | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717. | 0.491 |
| abrB | abbA | BSU00370 | BSU14120 | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.838 |
| abrB | sinI | BSU00370 | BSU24600 | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | 0.893 |
| abrB | sinR | BSU00370 | BSU24610 | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...] | 0.943 |
| abrB | slrA | BSU00370 | BSU38229 | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | Anti-repressor of SlrR; Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation. | 0.633 |
| abrB | spo0A | BSU00370 | BSU24220 | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.995 |
| mstX | abbA | BSU31321 | BSU14120 | Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer. | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.687 |
| mstX | veg | BSU31321 | BSU00440 | Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer. | Conserved hypothetical protein; Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity, independently of the SinI, SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation. | 0.890 |
| sinI | abbA | BSU24600 | BSU14120 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.682 |
| sinI | abrB | BSU24600 | BSU00370 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT. | 0.893 |
| sinI | sinR | BSU24600 | BSU24610 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...] | 0.999 |
| sinI | slrA | BSU24600 | BSU38229 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Anti-repressor of SlrR; Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation. | 0.919 |
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