STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cwlSPeptidoglycan hydrolase (cell wall-binding d,l-endopeptidase); Probably functions as a cell separation enzyme in addition to LytE and LytF. (414 aa)    
Predicted Functional Partners:
lytG
Exoglucosaminidase; Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Catalyzes the hydrolysis of 1,4-beta-linkages between N-acetyl-D-glucosamine and N- acetylmuramic acid residues in peptidoglycan. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division.
    
 0.956
cwlK
Murein L,D:-endopeptidase; Cleaves the linkage of the L-alanine-D-glutamic acid of B.subtilis cell wall; Belongs to the peptidase M15C family.
 
   
 0.793
sodC
Superoxide dismutase (exported lipoprotein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
  
    0.785
ywoF
Putative pectate lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.774
ylaE
Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
   
  
 0.757
yqaS
Putative phage-related terminase small subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
   
  
 0.683
yqaR
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.683
cwlO
Secreted cell wall DL-endopeptidase; The C-terminal part of CwlO shows a cell wall hydrolytic DL- endopeptidase activity; Belongs to the peptidase C40 family.
 
  
0.648
lytH
Sporulation-specific L-Ala-D-Glu endopeptidase; L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation.
 
  
 0.589
yoyG
Putative sporulation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
      
 0.574
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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