STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpGRhomboid protease glup; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter (507 aa)    
Predicted Functional Partners:
yqgQ
Uncharacterized protein YqgQ; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor
     
 0.951
glcK
Glucose kinase; Belongs to the ROK (NagC/XylR) family
     
 0.768
glcP
Mfs transporter, fhs family, glucose/mannose:h+ symporter; Can transport glucose, mannose, 2-deoxyglucose and methyl alpha-glucoside, but not galactose
   
  
 0.732
tufA
Elongation factor tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis
  
  
 0.720
htpG
Class iii heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity
  
 0.703
dinG
Damage inducible atp-dependent 3'->5' nuclease; 3'-5' exonuclease
  
 0.691
ftsH
Cell-division protein and general stress protein (class iii heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
  
 0.650
dnaK
Molecular chaperone dnak; Acts as a chaperone
  
 0.625
samT
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; In the C-terminal section; belongs to the methylenetetrahydrofolate reductase family
  
 
 0.621
ytjP
Succinyl-diaminopimelate desuccinylase; Putative dipeptidase YtjP; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
   
 
 0.612
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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