node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adeC | apt | BSU14520 | BSU27610 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.991 |
adeC | deoD | BSU14520 | BSU19630 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family. | 0.905 |
adeC | guaA | BSU14520 | BSU06360 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.458 |
adeC | guaC | BSU14520 | BSU32130 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (Probable). | 0.549 |
adeC | hprT | BSU14520 | BSU00680 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Hypoxanthine-guanine phosphoribosyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. | 0.944 |
adeC | pupG | BSU14520 | BSU23490 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. | 0.954 |
adeC | xpt | BSU14520 | BSU22070 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily. | 0.658 |
adeC | yerA | BSU14520 | BSU06560 | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Putative adenine deaminase YerA; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.949 |
apt | adeC | BSU27610 | BSU14520 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.991 |
apt | deoD | BSU27610 | BSU19630 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family. | 0.977 |
apt | gmk | BSU27610 | BSU15680 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.968 |
apt | guaA | BSU27610 | BSU06360 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.993 |
apt | guaC | BSU27610 | BSU32130 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (Probable). | 0.973 |
apt | hprT | BSU27610 | BSU00680 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. | 0.987 |
apt | pupG | BSU27610 | BSU23490 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. | 0.968 |
apt | purB | BSU27610 | BSU06440 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase; Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.941 |
apt | xpt | BSU27610 | BSU22070 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily. | 0.967 |
apt | yerA | BSU27610 | BSU06560 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative adenine deaminase YerA; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.970 |
deoD | adeC | BSU19630 | BSU14520 | Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family. | Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.905 |
deoD | apt | BSU19630 | BSU27610 | Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.977 |