STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
albDPutative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. (436 aa)    
Predicted Functional Partners:
albA
Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA.
  
  
 0.996
albC
Putative transporter involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin; Belongs to the ABC transporter superfamily.
  
 
 0.996
albB
Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin.
  
  
 0.992
albE
Putative hydrolase involved in subtilosin production; Involved in the production of the bacteriocin subtilosin.
  
 
 0.980
albF
Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin.
  
 
 0.967
albG
Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin.
  
  
 0.959
sboX
Putative bacteriocin-like product; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
    0.870
sboA
Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood.
  
  
 0.821
ywiB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
     
 0.635
yjbQ
Putative Na+/H+ antiporter; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.607
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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