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perR protein (Bacillus subtilis 168) - STRING interaction network
"perR" - Peroxide operon regulator in Bacillus subtilis 168
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Predicted Interactions
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textmining
co-expression
protein homology
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perRPeroxide operon regulator; Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA (145 aa)    
Predicted Functional Partners:
ahpC
Alkyl hydroperoxide reductase subunit C (EC-1.11.1.5); Directly reduces organic hydroperoxides in its reduced dithiol form (187 aa)
   
   
  0.965
katA
Vegetative catalase (EC-1.11.1.6); Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide (483 aa)
   
   
  0.936
zosA
Zinc-transporting ATPase; Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development (637 aa)
         
  0.927
mntR
Transcriptional regulator MntR; Central regulator of manganese homeostasis. In the presence of manganese, it mediates repression of the manganese transporter MntH; under low manganese conditions, it activates the transcription of the mntABCD operon (142 aa)
   
 
  0.909
mrgA
Metalloregulation DNA-binding stress protein; Forms highly stable, multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing (153 aa)
   
   
  0.908
sodA
Superoxide dismutase (EC-1.15.1.1); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (202 aa)
   
 
  0.887
ohrR
Organic hydroperoxide resistance transcriptional regulator; Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements (147 aa)
     
   
  0.886
trxB
Thioredoxin (EC-1.8.1.9) (316 aa)
         
  0.882
trxA
Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (104 aa)
   
 
  0.877
ahpF
NADH dehydrogenase (EC-1.6.99.3 1.8.1.-); Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (509 aa)
         
  0.871
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis, B. subtilis subsp. subtilis, B. subtilis subsp. subtilis str. 168, Bacillus globigii, Bacillus natto, Bacillus sp. 15:2, Bacillus sp. RSP-GLU, Bacillus sp. S2 BC-1, Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700, Bacillus subtilis/Bacillus globigii, Bacillus uniflagellatus, Vibrio subtilis
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