node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HemD | cobA | aq_1771 | aq_207 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.979 |
HemD | cysG | aq_1771 | aq_1237 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Siroheme synthase. | 0.404 |
HemD | dcuP | aq_1771 | aq_334 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.936 |
HemD | gsa | aq_1771 | aq_816 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde aminotransferase. | 0.687 |
HemD | hemA | aq_1771 | aq_1279 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.768 |
HemD | hemB | aq_1771 | aq_2109 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.952 |
HemD | hemC | aq_1771 | aq_263 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
aq_1277 | hemA | aq_1277 | aq_1279 | Putative protein. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.563 |
cobA | HemD | aq_207 | aq_1771 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.979 |
cobA | cysG | aq_207 | aq_1237 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Siroheme synthase. | 0.999 |
cobA | dcuP | aq_207 | aq_334 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.934 |
cobA | hemA | aq_207 | aq_1279 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.558 |
cobA | hemB | aq_207 | aq_2109 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.741 |
cobA | hemC | aq_207 | aq_263 | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.977 |
cydB | dcuP | aq_1358 | aq_334 | Cytochrome oxidase d subunit II. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.638 |
cydB | hemA | aq_1358 | aq_1279 | Cytochrome oxidase d subunit II. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.652 |
cydB | hemC | aq_1358 | aq_263 | Cytochrome oxidase d subunit II. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.619 |
cysG | HemD | aq_1237 | aq_1771 | Siroheme synthase. | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.404 |
cysG | cobA | aq_1237 | aq_207 | Siroheme synthase. | uroporphyrin-III c-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
cysG | gsa | aq_1237 | aq_816 | Siroheme synthase. | Glutamate-1-semialdehyde aminotransferase. | 0.876 |