node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aq_1349 | dpbF | aq_1349 | aq_1422 | Putative protein. | DNA polymerase beta family. | 0.532 |
dnaN | dpbF | aq_1882 | aq_1422 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase beta family. | 0.798 |
dnaN | hisIE | aq_1882 | aq_1968 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.413 |
dnaN | lig | aq_1882 | aq_1394 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA ligase (ATP dependent); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.994 |
dnaN | pol | aq_1882 | aq_1628 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase I 3'-5' exo domain; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.996 |
dpbF | aq_1349 | aq_1422 | aq_1349 | DNA polymerase beta family. | Putative protein. | 0.532 |
dpbF | dnaN | aq_1422 | aq_1882 | DNA polymerase beta family. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.798 |
dpbF | hisB | aq_1422 | aq_039 | DNA polymerase beta family. | Imidazoleglycerolphosphate dehydratase. | 0.528 |
dpbF | hisIE | aq_1422 | aq_1968 | DNA polymerase beta family. | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.748 |
dpbF | lig | aq_1422 | aq_1394 | DNA polymerase beta family. | DNA ligase (ATP dependent); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.951 |
dpbF | mutS2 | aq_1422 | aq_1242 | DNA polymerase beta family. | DNA mismatch repair protein MutS; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.740 |
dpbF | mutY1 | aq_1422 | aq_282 | DNA polymerase beta family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.509 |
dpbF | mutY3 | aq_1422 | aq_496 | DNA polymerase beta family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.509 |
dpbF | pdxJ | aq_1422 | aq_1423 | DNA polymerase beta family. | Pyridoxal phosphate synthetase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.564 |
dpbF | pol | aq_1422 | aq_1628 | DNA polymerase beta family. | DNA polymerase I 3'-5' exo domain; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.930 |
hisB | dpbF | aq_039 | aq_1422 | Imidazoleglycerolphosphate dehydratase. | DNA polymerase beta family. | 0.528 |
hisB | hisIE | aq_039 | aq_1968 | Imidazoleglycerolphosphate dehydratase. | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
hisIE | dnaN | aq_1968 | aq_1882 | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.413 |
hisIE | dpbF | aq_1968 | aq_1422 | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | DNA polymerase beta family. | 0.748 |
hisIE | hisB | aq_1968 | aq_039 | phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | Imidazoleglycerolphosphate dehydratase. | 0.999 |