node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrD1 | sqr | aq_695 | aq_2186 | Cation efflux system (AcrB/AcrD/AcrF family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. | 0.697 |
aq_788 | hupD | aq_788 | aq_667 | Putative protein. | HupD hydrogenase related function. | 0.733 |
aq_788 | sor | aq_788 | aq_455 | Putative protein. | Sulfur oxygenase reductase. | 0.900 |
aq_788 | sqr | aq_788 | aq_2186 | Putative protein. | Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. | 0.927 |
cyc | gltA | aq_042 | aq_150 | Cytochrome c. | Citrate synthase. | 0.805 |
cyc | soxB | aq_042 | aq_1803 | Cytochrome c. | Sulfur oxidation protein SoxB; Belongs to the 5'-nucleotidase family. | 0.783 |
cyc | sqr | aq_042 | aq_2186 | Cytochrome c. | Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. | 0.775 |
gap | gltA | aq_1065 | aq_150 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | Citrate synthase. | 0.730 |
gap | hupD | aq_1065 | aq_667 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | HupD hydrogenase related function. | 0.639 |
gap | hypA | aq_1065 | aq_1021 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | Hydrogenase accessory protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.643 |
gap | sqr | aq_1065 | aq_2186 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. | 0.638 |
gltA | cyc | aq_150 | aq_042 | Citrate synthase. | Cytochrome c. | 0.805 |
gltA | gap | aq_150 | aq_1065 | Citrate synthase. | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.730 |
gltA | hupD | aq_150 | aq_667 | Citrate synthase. | HupD hydrogenase related function. | 0.606 |
gltA | hypA | aq_150 | aq_1021 | Citrate synthase. | Hydrogenase accessory protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.605 |
gltA | sqr | aq_150 | aq_2186 | Citrate synthase. | Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. | 0.691 |
hupD | aq_788 | aq_667 | aq_788 | HupD hydrogenase related function. | Putative protein. | 0.733 |
hupD | gap | aq_667 | aq_1065 | HupD hydrogenase related function. | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.639 |
hupD | gltA | aq_667 | aq_150 | HupD hydrogenase related function. | Citrate synthase. | 0.606 |
hupD | hypA | aq_667 | aq_1021 | HupD hydrogenase related function. | Hydrogenase accessory protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.815 |