STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hksP4Histidine kinase sensor protein. (339 aa)    
Predicted Functional Partners:
phoB
Transcriptional regulator (PhoB-like).
 
 0.998
aq_1873
Putative protein.
  
 
 0.985
aq_1442
Hypothetical protein.
  
 
 0.971
aq_027
Hypothetical protein.
 
 
 0.949
hoxX
Hydrogenase regulation HoxX; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
 0.940
aq_1806
Putative protein.
   
 
 0.932
aq_1825
Putative protein.
  
 
 0.896
aq_1345
Putative protein.
    
 
 0.884
lpdA
Dihydrolipoamide dehydrogenase.
   
 0.791
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.720
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.