STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acrD1Cation efflux system (AcrB/AcrD/AcrF family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1082 aa)    
Predicted Functional Partners:
acrE
Acriflavin resistance protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.975
aq_699
Hypothetical protein.
   0.965
aq_986
Putative protein.
  
 
 0.762
aq_294
Putative protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.736
czcB2
Cation efflux system (czcB-like); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.722
sqr
Sulfide-quinone reductase; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family.
  
     0.697
merR
Transcriptional regulator (MerR family).
   
 
 0.656
dnaJ2
Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]
     
 0.616
queH
Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
       0.610
czcB3
Cation efflux system (czcB-like); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.607
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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