STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctrA1Cation transporting ATPase (E1-E2 family). (835 aa)    
Predicted Functional Partners:
ldhA
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
   0.844
mpg
Mannose-1-phosphate guanyltransferase.
  
  
 0.839
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity).
  
    0.814
aq_720
Hypothetical protein.
  
    0.768
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
  
    0.761
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
  
 0.755
malM
4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.
       0.752
mgtC
Mg(2+) transport ATPase.
  
 
 0.709
ccdA
Cytochrome c-type biogenesis protein.
  
    0.706
speC
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
     
 0.684
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.