node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aq_1996 | surE | aq_1996 | aq_832 | Hypothetical protein; Belongs to the CinA family. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
cmk | guaA | aq_2153 | aq_236 | Cytidylate kinase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.486 |
cmk | surE | aq_2153 | aq_832 | Cytidylate kinase. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.928 |
guaA | cmk | aq_236 | aq_2153 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cytidylate kinase. | 0.486 |
guaA | guaB | aq_236 | aq_2023 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | kad | aq_236 | aq_078 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.517 |
guaA | purA | aq_236 | aq_1290 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.883 |
guaA | purB | aq_236 | aq_597 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase. | 0.907 |
guaA | purH | aq_236 | aq_1963 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.877 |
guaA | pyrF | aq_236 | aq_1580 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.518 |
guaA | pyrH | aq_236 | aq_713 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.752 |
guaA | surE | aq_236 | aq_832 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.949 |
guaB | guaA | aq_2023 | aq_236 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | kad | aq_2023 | aq_078 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.401 |
guaB | purA | aq_2023 | aq_1290 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
guaB | purB | aq_2023 | aq_597 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate lyase. | 0.959 |
guaB | purH | aq_2023 | aq_1963 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.969 |
guaB | pyrH | aq_2023 | aq_713 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.440 |
guaB | surE | aq_2023 | aq_832 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.930 |
kad | guaA | aq_078 | aq_236 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.517 |