STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BB_0685hydroxymethylglutaryl-CoA reductase, degradative; Converts HMG-CoA to mevalonate. (431 aa)    
Predicted Functional Partners:
BB_0683
hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.
 
 
 0.999
mvk
Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549.
 
 0.998
mvaD
Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.
 
  
 0.988
BB_0109
acetyl-CoA acetyltransferases subfamily; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.980
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
    
 0.970
BB_0687
Phosphomevalonate kinase, putative; Identified by match to protein family HMM PF00288.
 
   
 0.959
BB_0334
Oligopeptide transport ATP-binding protein OppD; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; Belongs to the ABC transporter superfamily.
      
 0.828
BB_0314
Octaprenyl-diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
 
 0.725
BB_0335
OppF; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; Belongs to the ABC transporter superfamily.
      
 0.607
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.594
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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