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pnp protein (Brucella melitensis) - STRING interaction network
"pnp" - Polyribonucleotide nucleotidyltransferase in Brucella melitensis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pnpPolyribonucleotide nucleotidyltransferase (EC-2.7.7.8); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (714 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone (637 aa)
   
  0.909
eno
Phosphopyruvate hydratase (EC-4.2.1.11); Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (425 aa)
   
 
  0.901
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (959 aa)
   
 
  0.900
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA (89 aa)
 
 
  0.886
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (694 aa)
   
 
  0.881
rpoB
DNA-directed RNA polymerase, beta subunit (EC-2.7.7.6); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1377 aa)
   
  0.868
rpoA
DNA-directed RNA polymerase, alpha subunit (EC-2.7.7.6); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (337 aa)
   
  0.866
BMEI0463
Poly(A) polymerase / tRNA nucleotidyltransferase (423 aa)
     
 
  0.864
BMEI0934
ATP-dependent RNA helicase rhle (510 aa)
   
 
  0.858
BMEI1035
ATP-dependent RNA helicase dead (482 aa)
   
 
  0.858
Your Current Organism:
Brucella melitensis
NCBI taxonomy Id: 224914
Other names: B. melitensis, B. melitensis bv. 1, B. melitensis bv. 1 str. 16M, Brucella melitensis, Brucella melitensis ATCC 23456, Brucella melitensis biovar 1, Brucella melitensis bv. 1, Brucella melitensis bv. 1 str. 16M, Micrococcus melitensis, Streptococcus Miletensis
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