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nanM protein (Brucella melitensis) - STRING interaction network
"nanM" - N-acetylneuraminate epimerase in Brucella melitensis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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nanMN-acetylneuraminate epimerase; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family (394 aa)    
Predicted Functional Partners:
nanEK
Bifunctional enzyme NanE/NanK; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P); In the N-terminal section; belongs to the NanE family (518 aa)
 
   
  0.973
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (434 aa)
           
  0.576
BMEII0855
annotation not available (91 aa)
              0.574
BMEII0858
annotation not available (242 aa)
         
  0.570
BMEII0859
Putative ABC transporter peptide-binding protein BMEII0859; Probably part of an ABC transporter complex that could be involved in peptide import (500 aa)
              0.410
Your Current Organism:
Brucella melitensis
NCBI taxonomy Id: 224914
Other names: B. melitensis bv. 1 str. 16M, Brucella melitensis, Brucella melitensis ATCC 23456, Brucella melitensis bv. 1 str. 16M
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