STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupADNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. (92 aa)    
Predicted Functional Partners:
pheA
P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
     
 0.744
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.702
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.658
thrA
Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family.
     
 0.617
polA
Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.
   
 
 0.603
fliG
Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
    
   0.580
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
    
   0.580
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC.
       0.570
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
   0.570
cspE
COG1278; CSP-A; cold shock protein; CS7.4.
  
 
 0.522
Your Current Organism:
Buchnera aphidicola Bp
NCBI taxonomy Id: 224915
Other names: B. aphidicola str. Bp (Baizongia pistaciae), Buchnera aphidicola (subsp. Baizongia pistaciae), Buchnera aphidicola str. Bp (Baizongia pistaciae)
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