STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V3ZQD3_LOTGINon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (339 aa)    
Predicted Functional Partners:
V4A2Q5_LOTGI
Phorbol-ester/DAG-type domain-containing protein.
   
 0.999
V4A9M3_LOTGI
MAGE domain-containing protein.
   
 0.998
V4B542_LOTGI
SMC_N domain-containing protein.
   
 0.998
V3Z5G5_LOTGI
SP-RING-type domain-containing protein.
    
 0.996
V4AH43_LOTGI
AAA_23 domain-containing protein.
   
 0.966
V4CM18_LOTGI
SMC_N domain-containing protein.
   
 0.966
V3ZYT8_LOTGI
SMC_N domain-containing protein.
   
 0.908
V4AFJ6_LOTGI
SMC hinge domain-containing protein.
   
 0.849
V4CJ70_LOTGI
Uncharacterized protein.
   
 0.832
V4B263_LOTGI
SMC hinge domain-containing protein.
   
 0.808
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.