STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4ALE7_LOTGITranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1520 aa)    
Predicted Functional Partners:
V4BFV9_LOTGI
TFIIS N-terminal domain-containing protein.
   
 0.969
V4AJ42_LOTGI
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.962
V3ZZB8_LOTGI
Uncharacterized protein.
   
 0.949
V4A8E4_LOTGI
Transcription elongation factor SPT5.
   
 0.937
V4BLS6_LOTGI
Uncharacterized protein.
   
 0.919
V4B4X5_LOTGI
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.915
V4B3V0_LOTGI
RPOLD domain-containing protein.
    
 0.905
V4ARM6_LOTGI
TPR_REGION domain-containing protein.
   
 0.902
V4B5I5_LOTGI
S1 domain-containing protein.
    
 0.899
V3ZW05_LOTGI
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.887
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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